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Levothyroxine

An underactive thyroid (hypothyroidism).

General information only, not medical advice, and no doses. Read the leaflet in your pack and ask a pharmacist about your own situation, other medicines, pregnancy or any health condition.

At a glance

Generic nameLevothyroxine (thyroid hormone)
TypeThyroid hormone replacement
Commonly used forAn underactive thyroid (hypothyroidism).
With food?Taken on an empty stomach; keep it well apart from calcium, iron and some foods and drinks that reduce how much is absorbed.
AlcoholNo direct interaction with the occasional drink.
TimingUsually first thing in the morning, about 30–60 minutes before breakfast, at the same time each day.

Food and drink

Taken on an empty stomach; keep it well apart from calcium, iron and some foods and drinks that reduce how much is absorbed. No direct interaction with the occasional drink.

When to take it

Usually first thing in the morning, about 30–60 minutes before breakfast, at the same time each day.

Good to know

The dose is fine-tuned with blood tests, so take it consistently and do not change it yourself. If anything about your own use is unclear, a pharmacist can advise for free.

Other common medicines

Paracetamol

Mild to moderate pain such as headache, toothache and muscle aches, and lowering a fever.

Ibuprofen

Pain, inflammation and fever — for example period pain, sprains, back pain and dental pain.

Aspirin

Pain and fever at normal doses; a low daily dose is used, only on medical advice, to reduce clotting risk.

Naproxen

Pain and inflammation, including muscle and joint pain and period pain; it is longer-acting than ibuprofen.

Omeprazole

Heartburn, acid reflux and stomach or gut ulcers.

Loratadine

Hay fever and other allergies, and itchy hives.

Source: General medicine information paraphrased from standard patient-information-leaflet guidance. Always read the leaflet in your pack. · checked 2026-09-04

Frequently asked questions

What is Levothyroxine used for?

An underactive thyroid (hypothyroidism).

Can I drink alcohol with Levothyroxine?

No direct interaction with the occasional drink.

Should I take Levothyroxine with food?

Taken on an empty stomach; keep it well apart from calcium, iron and some foods and drinks that reduce how much is absorbed.

See the pattern over time

TempoLife logs symptoms, food and sleep, so you can bring a clear picture to your pharmacist or doctor.

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